Does X115+Plus ® Work? - Complete Review


In this article we'll be talking about the anti-aging supplement X115®+Plus New Generation Skin Care. Read the complete review on this product, and you'll learn what is it for, what's in it, how to use it, how much does it cost and where to buy it.

Also, we're going to compare X115®+Plus with other anti-aging products, in order to understand which anti-wrinkle supplements are the best on the market.

What is it?

What is X115®+Plus?

X115®+Plus is an anti-aging food supplement produced by the Italian Jarmy s.r.l., a company located in Scandiano (Reggio Emilia) that works in the production of anti-aging nutricosmetic products.

The product is 100% made in Italy and consists of 2 supplements in a single product: ready to drink vials (to be taken in the morning) and packets to be dissolved in water (to be taken in the evening, before going to bed).

X115 Collagene X115®+Plus is characterized by a shock formulation with a high concentration of active substances, the use of which is designed to intensively nourish the skin from the inside while performing an anti-wrinkle and regenerating action. In addition, thanks to its particular and rich composition, X115®+Plus also contributes in the maintenance of the health of nails, hair and joints.


Which ingredients does X115®+Plus contain?

This is the ingredients list provided on the package of X115®+Plus.

Day Vials

Measuring cap: Maltodextrin; Vitamin E Acetate; Astaxanthin from Haematococcus pluvialis; Lipoic acid; Coenzyme Q10; Vitamin B6; silicon dioxide; Biotin. Vial: purified water; fructose; Polygonum dry extract (Polygonum cuspidatum Siebold & Zucc. root) Resveratrol 98%; Echinacea cell colture extract (Echinacea angustifolia DC. root) Echinacoside 4%; orange aroma; Cocoa dry extract (Theobroma cacao L. seeds) Polyphenols 40%; Pomegranate dry extract (Punica granatum L. fruits) Ellagic acid 20%; potassium sorbate, sodium benzoate; citric acid; Olive dry extract (Olea europaea L. leaves) Oleuropein 6%; xanthan gum.


Hydrolyzed fish collagen; maltodextrin; vitamin C; citric acid; red orange aroma; Centella dry extract (Centella asiatica L. herba) Triterpene derivatives 10%; Sodium hyaluronate (Hyaluronic acid); orange aroma; lemon flavor; Zinc gluconate; Copper gluconate; sucralose; Vitamin D3; Folic acid. Allergens: Contains fish derivatives

The active ingredients that characterize the supplement are those highlighted in bold. The remaining ingredients are the so-called excipients, substances without any anti-aging property, used purely to convey the above-mentioned active ingredients.

The active ingredients found above are also listed in the table below, which shows the nutritional values of the product:

1 Vial VNR*
Polygonum cuspidatum radice e.s.
  of which resveratrol
Echinacea angustifoglia radice e.s.
  of which echinacosid
Theobroma cacao semi e.s.
  of which polyphenols
Punica granatum frutti e.s.
  of which ellagic acid
Olea euroapea frutti e.s.
  of which oleuropein
Vitamin E (Tocoferolo acetato) 15 mg 125%
Lipoic acid 12,50 mg -
Coenzyme Q10 12,50 mg -
Vitamin B6 2 mg 143%
Astaxanthin 1 mg -
Biotin 0,1 mg 200%
1 Sachet VNR*
Hydrolized fFish Collagen 5.000 mg -
Vitamin C 300 mg 375%
Centella asiatica, plant e.s.
  contain total triterpene derivatives
Hyaluronic acid 100 mg -
Zinc 5 mg 50%
Copper 1 mg 100%
Folic Acid 100 mcg 50%
Vitamin D3 2 mcg 40%
*Reference Nutritional Values

Looking at the ingredients contained within the supplement, we can say that the vials for the morning play a predominantly antioxidant action, while the packets for the evening show more of a nutritional aspect for our skin.

Active substances

Detailed information on the active ingredients contained in X115®+Plus

Now that we've seen what ingredients are present in the X115®+Plus supplement, let's look into the details of each one of the active ingredients. In this way, we will be able to comprehend in what way this supplement can help us in the fight against the signs of the aging process.

Hydrolyzed marine collagen

Collagen is a large protein that - along with elastic fibers and glycosaminoglycans (a group of substances to which hyaluronic acid belongs) - constitutes the structure that supports our skin at the dermis level (the intermediate layer of our skin).

Specifically, collagen gives the skin strength, tone and firmness.

However, the aging process causes the production of this precious element to decrease more and more, while the one already formed suffers alterations and degrades faster. The combination of all these phenomena favors the appearance of wrinkles and the signs of time in general.

The collagen contained within X115®+Plus is of marine origin and has undergone a particular process, called "enzymatic hydrolysis". This process is carried out in order to break this large protein, obtaining smaller fragments (hydrolysed collagen) that can be absorbed more easily by the body.

The collagen fragments obtained from this process help to restore skin firmness while promoting the synthesis of new molecules of this precious element.

Hyaluronic acid

Hyaluronic acid contributes to the formation of the structure that supports our skin. In particular, it's very useful in the maintenance of hydration, since it's able to bind and retain large amounts of water.

Polyphenols from Olive and Cocoa

Polyphenols (bio-polyphenols) obtained from olive and cocoa are particular substances with strong antioxidant properties. This is essential to counteract the harmful action of free radicals.

Free radicals are highly reactive chemical species that cause the so-called "oxidative stress", in the cells of our skin, damaging them and its structure, causing the appearance of wrinkles and other marks.

Free radicals, in fact, are one of the main factors responsible for skin aging.

Also, polyphenols help to protect cells from photo-aging (UV rays are able to produce high levels of free radicals, causing premature skin aging).

Vitamins C and E

These are the antioxidant vitamins for excellence, they are very useful in counteracting the harmful action of free radicals and, at the same time, they protect the skin from premature aging due to excessive and uncontrolled exposure to UV rays (photo-aging).

Vitamin C is also involved in the synthesis of new collagen.

Alpha-lipoic acid

Alpha-lipoic acid is also an antioxidant active ingredient with a sort of double action. In fact, in addition to directly counteracting oxidative stress induced by free radicals, it's also capable of regenerating other antioxidant active principles, such as the above-mentioned vitamins C and E.


Resveratrol is a molecule with interesting antioxidant properties, combined with the ability to protect cells from aging. It also helps to counteract the loss of skin elasticity.

Echinacea Extract

Echinacea angustifolia extract is rich in echinacoside, a substance that has been shown to prevent hyaluronic acid degradation and to stimulate the activity of fibroblasts. The latter are the cells of the dermis that are responsible for the synthesis of the elements that make up the structure of our skin: collagen, elastic fibers and glycosaminoglycans (including hyaluronic acid).

In addition, the echinacea extract is well known for its immunostimulant properties.

Centella Extract

Centella asiatica extract, rich in triterpene derivates, has been shown to stimulate the production of collagen and fibronectin by fibroblasts, while counteracting the damaging action of free radicals and inflammatory processes.

Centella extract also has a beneficial effect on the blood microcirculation.

Zinc and Copper

Zinc and copper are essential micronutrients for the well-being of our skin and our body in general.

Zinc, in fact, helps to protect the cells from oxidative stress, and it's directly involved in the processes of cell division and DNA synthesis.

Similarly, copper helps to protect cells from oxidative stress.

Additionally, both of these elements contribute to strengthening immune defenses and - along with vitamin C - they are involved in the synthesis of new collagen.


The X115®+Plus pack is particularly elegant. In fact, it's a white box with the gold logo of the brand on the upper side, with many small Xs embossed and a tamper-proof seal.

Inside the box there are both the Day Vials and the Night Packets.

Buy X115®+Plus2 on Amazon or visit the X115 official website

The box contains 15 vials of 15 ml each and 15 sachets of 9 grams each, sufficient for 15 days of the shock treatment.

Method of use

It's recommended that you take a Day Vial in the morning (at breakfast) and a Night Packet in the evening, just before going to sleep.

Before taking the vial, you should shake it for a few seconds in order to redistribute any deposits that may have formed (but which do not alter the quality of the product in any way). Then, the contents of the vial may be taken as is, or diluted in water (in particular, it's recommended to perform this operation if you are suffering from gastric hyperacidity).

As for the bags, instead, their contents must be dissolved in water beforehand.

Duration of the treatment

For how long should I take X115®+Plus?

X115®+Plus has a highly concentrated shock formulation. For this reason, it's recommended that you take it for the first 30 to 90 days of treatment.

After this period, you can continue with a maintenance treatment that can be done in two different ways:

  • Continuing to take X115®+Plus on alternate days (halving the frequency);
  • Taking the X115® Primarysupplement every day, which is specially designed for the maintenance phase.

The daily intake of X115®+Plus can be resumed during stressful periods and after a strong sun exposure to protect the skin from photo-aging.

Finally, very important, if you decide to stop the treatment with X115®+Plus it's crucial not to do so abruptly, you should gradually reduce the doses in the span of two to three weeks.

Clinical studies

The official site of the product provides the results of a few clinical trials conducted on X115® in order to evaluate its effectiveness.

These studies found that - as a result of continued use of the product - a significant increase in collagen density at the dermis level. This increase becomes even more significant if - in conjunction with the supplement - the X115® New Generation Cream is consistently used. This cream is specially formulated to ensure the possibility of a complete anti-wrinkle treatment that acts both from the inside and from the outside (the "IN & OUT" approach). Positive results were also obtained with regard to increased hydration and skin elasticity, with a high index of satisfaction and subjective perception of results by the users enrolled in the studies.


The Day Vials of X115®+Plus are extremely practical to use since - being ready to drink - they can be taken without any problems wherever you happen to be.

On the contrary, the packets need to be dissolved in water, which is not very practical. On the other hand, compared to the liquid formulation, they have the advantage of better preservability and protection of active ingredients. However, given the large amount of active substances provided by these bags, I consider that their relative inconvenience is a more than acceptable "price to pay".


The list price of the X115®+Plus supplement is 64 euros for a package (with 15 vials and 15 packets) enough to complete 15 days of shock treatment, or 30 days of maintenance treatment (taking the supplement on alternate days).

Where to Buy it?

X115®+Plus is available in Italy in all accredited pharmacies and para-pharmacies, you can find the list on the manufacturer's website, or by clicking here.

In addition, X115®+Plus is readily available online, on the official website and on Amazon.X115 su Amazon

Supplements in Comparison

Let's dive into the comparison between various anti-aging supplements that I consider the best on the market.

In order to make things easier, I've prepared the table below:

    X115®+PLUS2 Gold Collagen®
List price Euro 62 42
Days of Treatment Euro 15 10
Cost per day of treatment Euro 4,13/3,8* 4,20
Hydrolyzed marine collagen g 5 5
Hyaluronic acid mg 100 20
Vitamin C mg 300 80
Resveratrol mg 147 Not present
Alpha lipoic acid mg 12,5 Not present
Coenzyme Q10 mg 12,5 Not present
Polyphenols from Cocoa mg 12 Not present
Oleuropein (from olive leaves) mg 0.96 Not present
Ellagic acid (from pomegranate) mg 5 Not present
Astaxanthin mg 1 Not present
Vitamin E mg 15 6
Biotin mcg 100 50
Vitamin B6 mg 2 1,4
Folic acid mcg 100 Not present
Vitamin D3 mcg 2 Not present
Zinc mg 5 1.5
Copper mg 2 0.15
Echinacoside from Echinacea a. mg 3,2 Not present
Triterpene derivates from Centella asiatica mg 30 Not present
* price excluding the commercial value of the free sample of anti-wrinkle cream

I don't think I'm exaggerating by saying that the table could speaks for itself. As a matter of fact, it's immediately clear which supplement has the most active substances quantity and concentration: X115®+Plus, followed immediately by the X115® Primary maintenance formulation.

It's true that the collagen content of X115®+Plus is slightly lower than the one in the Pure Gold Collagen® supplement; however, there are high concentrations of antioxidant substances, along with hyaluronic acid and centella and echinacea extracts, capable of stimulating fibroblasts to produce new collagen, new elastic fibers and new glycosaminoglycans.

It's precisely this rich composition - both qualitative and quantitative - that drives me to believe that the X115®+Plus supplement is the best anti-wrinkle supplement currently available on the market. In fact, the great variety of ingredients contained in it allows to fight wrinkles and the signs of time on multiple fronts, addressing the problem in all of its different aspects (free radicals, diminished fibroblast activity, photo-aging, etc.).

X115®+Plus doesn't only contrast the harmful action of free radicals but it also protects the skin from photo-aging, preserves hyaluronic acid from degradation, stimulates fibroblast activity, contributes to the maintenance of firmness, elasticity and skin tone, while maintaining the health of nails, hair and joints.

The Rankings

Since I was lucky enough to try all of the supplements we compared, I think I should be able to provide a rating on aspects that are very important to me in determining which anti-wrinkle supplement you should buy.

In this regard, I created the following table with my rankings, in which I gave a grade from 1 to 4 for each entry, as explained here:

  • Grade 1 = Insufficient
  • Grade 2 = Sufficient
  • Grade 3 = Good
  • Grade 4 = Excellent
Characteristics X115®+Plus X115®Primary Imedeen Prime RenewalTM Gold Collagen®
Availability 4 4 4 4
Practicality Day Vials: 4 3 3 4
Night Packets: 2
Taste and Flavor 3 4 4 3/4
Quantity of active substances 4 3/4 3 3
Quality/Price Ratio 4 4 2 2/3

Of course, even in my rankings, the X115® supplements show their superiority to the "opponents". In fact, X115®+Plus earns the highest score both for the richness of active substances and the quality/price ratio. It's true that the price of treatment with X115®+Plus is slightly higher than that of other anti-wrinkle supplements, but if we analyze more closely the actual content of active ingredients, in my opinion, we can see that it's actually cheaper.

As for practicality, Day Vials reach the top of the score, as opposed to the Night Packets whose use can be considered uncomfortable by many people.

Finally, X115®+Plus passes the "Taste and Flavor" test. In fact, its taste is certainly not the best, but on the other hand, with such high concentration of active substances, you can't expect a perfect taste.

Pros and Cons

X115®+Plus Pros

  • Contains high concentrations of collagen and hyaluronic acid.
  • There are many active antioxidants in high concentrations.
  • Presence of plant extracts (echinacea and centella) that stimulate the activity of fibroblasts, hence the production of collagen, elastic fibers and glycosaminoglycans.
  • It contributes to the well-being of nails, hair and joints.
  • Supports the body's immune defense (thanks to echinacea extract, vitamin C and zinc).
  • Protects the skin from photo-aging.
  • Does not contain lactose, colorants, GMOs, BSE-TSE.
  • Gluten free.
  • The Day Vials are definitely practical to use.
  • The value for money, in my opinion, is great.

X115®+Plus Cons

  • The flavor is not the best, although - given the high concentration of active substances - I think that it should be considered normal.
  • The practical use of the Night Packets isn't optimal. In addition, some may consider it to be negligible to divide the integrator into morning and evening.
  • Slightly high price, but in any case in line with other similar high-end products, and indeed more convenient if compared to the concentration of the active ingredients contained.


Since X115®+Plus contains marine collagen, its use is not suitable for vegetarians or vegans.

In addition, since the collagen derives from fish processing and the supplement contains soy-based products, the use of X115®Plus is contraindicated in subjects with allergies to fish, molluscs, crustaceans and soybean.

As a precaution, the use of X115®+Plus is contraindicated also during pregnancy, duringlactation and under 14 years of age.

Finally, due to the generous presence of lipoic acid, if you are being treated with hypoglycaemic drugs or any other medication, you must ask your doctor's advice before taking the supplement.

My opinion

If it wasn't clear yet, my opinion about the X115®+Plus supplement is more than positive!

As I said already, I believe that this anti-wrinkle supplement is the best that the market can offer right now. Not only for its rich composition, but also for the results that can be achieved with its use.

In fact, after the first month of use, I noticed the first improvements on the skin of my face, which appeared more hydrated and elastic. Such improvements, among other things, have also occurred on the skin of the whole body and, in particular, on the arms and belly.

Continuing the treatment and completing the full three-month (90-day) cycle recommended by the manufacturer, I achieved remarkable results. At the end of the treatment, my skin - as well as hydrated and elastic - has regained luminosity, tone and firmness, giving my face a more relaxed and rejuvenated appearance.

X115 Collagene

Buy X115®+Plus2 on Amazon or visit the X115 official website

At the same time, I noticed improvements in the toughness of my nails: before taking the product they tended to crumble, while at the end of the treatment I felt like they were more resistant than usual. Likewise, my hair - usually fragile and easy to break - seemed better to me, more robust, and fuller.

Finally, with regard to the results on wrinkles and the signs of time, I got the best results when I combined X115®+Plus with X115® New Generation Cream for Woman. The lines of expression and the less profound wrinkles, in fact, have visibly flattened (although, of course, they didn't disappeared altogether).

Certainly, these results have been possible thanks to the innovative "IN & OUT" approach, provided by X115® , which allows us to provide to our skin all the substances it needs to counter the signs of time, both from the inside (with the supplement), and from the outside (with the special cream).

In conclusion, I believe that the X115®+Plus supplement is a very good product that allows us to achieve tangible and remarkable results, as it's able to act effectively on the many factors that cause the much-feared aging of our skin.

Liquid Collagen

Buy X115®+Plus2 on Amazon or visit the X115 official website

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